Biocatalysis is the use of enzymatic reactions in the forms of isolated enzymes or in whole cells to catalyze chemical reactions. The use of enzymatic reactions in chemical production can contribute to greener and cleaner industries. With the catalytic power of enzymes, the process can be operated under mild pH and temperature, and avoid the creation of hazardous intermediates and waste.
GREEN CHEMISTRY & WHITE BIOTECHNOLOGY
CO2 emission from industrial processes is one of major factors contributing to global warming and climate change. Many production processes also generate toxic waste that is toxic to human health and environment. Toxic waste treatment processes add significant cost to the manufacturing industry. The use of enzymatic reactions in chemical production can contribute to greener and cleaner industries. With the catalytic power of enzymes, processes can be operated under mild pH and temperature
BIOCATALYSIS AT VISTEC
Our research team at VISTEC has a wide range of specialty enzymes including oxygenases, halogenases, dehalogenases, oxidases, reductases, dehydrogenases, aldolases, and hydratases that can catalyze regio- or stereo-specific redox, C-C bond condensation and group addition. These enzymatic reactions are often coupled in the form of cascade reactions to allow cofactor or substrate regeneration to reduce cost in large scale production.
We also study reaction mechanisms and structural features affecting the catalysis of these enzymes. Rational engineering and directed evolution are carried out to create engineered enzymes that perform better than the natural wild-type enzymes for specific tasks.